Located in the UNESCO World Heritage site of the Medieval Town of Rhodes, Fluvian Mansion is nestled on a quiet cobblestone street. It is within walking distance of significant landmarks such as the Palace of the Grand Master, the Street of the Knights, and the Archaeological Museum. Just down the street, you'll find a range of shops, cafes, restaurants, and bars. The mansion is also next to D'Aboise Gate, one of the impressive gates that connect the Old Town to the city center and its beaches.

The mansion boasts a historically rich location, sitting next to the St. George Bastion, one of Europe's most significant medieval trenches. Fluvian Mansion is conveniently located 700m from downtown Rhodes, 1.3km from the popular Elli Beach, 650m from Kolona Harbor, 2km from Acandia Port, and 16km from Diagoras International Airport. Its location provides easy access to both the historical charm of Rhodes and the modern conveniences of the city.